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Targeted Allele Detail
Symbol: Crtamtm1Achn
Name: cytotoxic and regulatory T cell molecule; targeted mutation 1, Andrew C Chan
MGI ID: MGI:3834613
Gene: Crtam  Location: Chr9:40972753-41004628 bp, - strand  Genetic Position: Chr9, 21.79 cM
Germline Transmission:  Earliest citation of germline transmission: J:145314
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA LacZ/neo cassette replaced exon 1 of the gene locus, deleting the ATG start site. No protein was detected in CD4+ or CD8+ T cells by immunoblot or flow cytometry assays. (J:145314)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Crtam Mutation:  10 strains or lines available
Original:  J:145314 Yeh JH, et al., Regulation of a late phase of T cell polarity and effector functions by Crtam. Cell. 2008 Mar 7;132(5):846-59
All:  1 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.10
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