About   Help   FAQ
The MGI survey is now closed.
Thanks for your support!
Tg(Ly6a-BCR/ABL1)IS1BIsg
Transgene Detail
Nomenclature
Symbol: Tg(Ly6a-BCR/ABL1)IS1BIsg
Name: transgene insertion IS1B, Isidro Sanchez-Garcia
MGI ID: MGI:3834463
Synonyms: IS1B
Transgene: Tg(Ly6a-BCR/ABL1)IS1BIsg  Location: unknown  
Transgene
origin
Strain of Origin:  (CBA x C57BL/6J)
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Ly6a-BCR/ABL1)IS1BIsg expresses 2 genes
 
Mutation detailsThe promoter was used to drive hematopoietic stem cell-specific expression of a human BCR-ABL1p210 fusion. Two lines were created (IS1A and IS1B) that exhibit similar phenotypes. (J:144382)
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Disease models
Loading...
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:144382 Perez-Caro M, et al., Cancer induction by restriction of oncogene expression to the stem cell compartment. EMBO J. 2009 Jan 7;28(1):8-20
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
01/20/2015
MGI 5.21
The Jackson Laboratory