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P2rx4tm1Dgen
Targeted Allele Detail
Nomenclature
Symbol: P2rx4tm1Dgen
Name: purinergic receptor P2X, ligand-gated ion channel 4; targeted mutation 1, Deltagen
MGI ID: MGI:3834163
Synonyms: P2X4-
Gene: P2rx4  Location: Chr5:122707544-122729738 bp, + strand  Genetic Position: Chr5, 62.53 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:145232
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129P2/OlaHsd
Project Collection: Deltagen
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe coding region of exon 2 was replaced with a lacZ and neo cassette. The absence of transcript expression was confirmed by quantitative RT-PCR of macrophage extracts. (J:145232)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any P2rx4 Mutation:  11 strains or lines available
References
Original:  J:145232 Brone B, et al., P2X currents in peritoneal macrophages of wild type and P2X4 -/- mice. Immunol Lett. 2007 Nov 15;113(2):83-9
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/30/2021
MGI 6.16
The Jackson Laboratory