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Supv3l1tm2.3Jkl
Targeted Allele Detail
Nomenclature
Symbol: Supv3l1tm2.3Jkl
Name: suppressor of var1, 3-like 1 (S. cerevisiae); targeted mutation 2.3, Jan Klysik
MGI ID: MGI:3833743
Synonyms: Supv3L1tm5Jkl
Gene: Supv3l1  Location: Chr10:62429209-62449738 bp, - strand  Genetic Position: Chr10, 32.4 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:144991
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsGerm line, cre mediation was used to remove exon 14 from Supv3l1tm2.1Jkl. The neo cassette remains. (J:144991)
Targeting the Supv3l1 allele to generate the Supv3l1tm2Jkl, Supv3l1tm2.1Jkl, Supv3l1tm2.2Jkl, and Supv3l1tm2.3Jkl alleles
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Supv3l1 Mutation:  11 strains or lines available
References
Original:  J:144991 Paul E, et al., Disruption of Supv3L1 damages the skin and causes sarcopenia, loss of fat, and death. Mamm Genome. 2009 Feb;20(2):92-108
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory