Npsr1^tm1Bhk
Targeted Allele Detail

Summary

• Symbol: Npsr1^tm1Bhk
• Name: neuropeptide S receptor 1; targeted mutation 1, Beverly H Koller
• MGI ID: MGI:3832372
• Synonyms: Gpra^-
• Gene: Npsr1 Location: Chr9:24009292-24227694 bp, + strand Genetic Position: Chr9, 9.99 cM
• Alliance: Npsr1^tm1Bhk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:144688
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 4 was replaced with a neo cassette. Northern blot analysis confirmed the expression of a truncated transcript. (J:144688)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Npsr1 Mutation: 37 strains or lines available

References

• Original: J:144688 Allen IC, et al., Expression and function of NPSR1/GPRA in the lung before and after induction of asthma-like disease. Am J Physiol Lung Cell Mol Physiol. 2006 Nov;291(5):L1005-17
• All: 11 reference(s)