Tg(Acta2-cre/ERT2)12Pcn
Transgene Detail
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Symbol: |
Tg(Acta2-cre/ERT2)12Pcn |
Name: |
transgene insertion 12, Pierre Chambon |
MGI ID: |
MGI:3831907 |
Synonyms: |
SMA-Cre-ERT2, tg(Sma-CreERT2)12Pcn |
Transgene: |
Tg(Acta2-cre/ERT2)12Pcn Location: unknown
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Alliance: |
Tg(Acta2-cre/ERT2)12Pcn page
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Transgene Type: |
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Transgenic (Inducible, Recombinase) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Tg(Acta2-cre/ERT2)12Pcn expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Acta2 (MGI:87909) |
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Mutation details: A construct containing cre fused to ERT2 followed by an frt flanked PGK-neo cassette was inserted at the initiation codon of Acta2 in a 175 kb mouse BAC. Tamoxifen-induced cre activity was seen in smooth muscle cells.
(J:144642)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Acta2
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:144642 Wendling O, et al., Efficient temporally-controlled targeted mutagenesis in smooth muscle cells of the adult mouse. Genesis. 2009 Jan;47(1):14-8 |
All: |
15 reference(s) |
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