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Lig4tm1Pmc
Targeted Allele Detail
Nomenclature
Symbol: Lig4tm1Pmc
Name: ligase IV, DNA, ATP-dependent; targeted mutation 1, Peter J McKinnon
MGI ID: MGI:3831168
Synonyms: Lig4LoxP, Lig IVloxP, pLig4LoxP
Gene: Lig4  Location: Chr8:9970020-9976323 bp, - strand  Genetic Position: Chr8, 4.52 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:144172
Parent Cell Line:  W9.5/W95 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    The open reading frame was flanked with loxP sites. (J:144172)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lig4 Mutation:  10 strains or lines available
References
Original:  J:144172 Shull ER, et al., Differential DNA damage signaling accounts for distinct neural apoptotic responses in ATLD and NBS. Genes Dev. 2009 Jan 15;23(2):171-80
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory