Srrtm1(cre/PGR)Himo
Targeted Allele Detail
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Symbol: |
Srrtm1(cre/PGR)Himo |
Name: |
serine racemase; targeted mutation 1, Hisashi Mori |
MGI ID: |
MGI:3831132 |
Gene: |
Srr Location: Chr11:74797185-74816774 bp, - strand Genetic Position: Chr11, 45.76 cM, cytoband B4
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Alliance: |
Srrtm1(cre/PGR)Himo page
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Germline Transmission: |
Earliest citation of germline transmission:
J:144537
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Parent Cell Line: |
RENKA (ES Cell)
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Strain of Origin: |
C57BL/6N
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Allele Type: |
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Targeted (Inducible, Null/knockout, Recombinase) |
Inducer: |
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mifepristone |
Mutations: |
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Duplication, Insertion
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Srrtm1(cre/PGR)Himo involves 1 genes/genome features (Srr)
View all
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Srrtm1(cre/PGR)Himo expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: A fusion of cre and human progesterone receptor followed by a neo cassette and genomic sequence spanning exons 3 through 9 was inserted upstream of exon 3. Exons 3 through 9 are duplicated. The absence of protein expression was confirmed by western blot analysis on brain extracts.
(J:144537)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Srr
(mouse)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Srr Mutation: |
32 strains or lines available
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Original: |
J:144537 Miya K, et al., Serine racemase is predominantly localized in neurons in mouse brain. J Comp Neurol. 2008 Oct 20;510(6):641-54 |
All: |
10 reference(s) |
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