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Targeted Allele Detail
Symbol: En2tm7.1Alj
Name: engrailed 2; targeted mutation 7.1, Alexandra L Joyner
MGI ID: MGI:3831095
Synonyms: En2GFPloxIRES
Gene: En2  Location: Chr5:28165694-28172166 bp, + strand  Genetic Position: Chr5, 13.94 cM
Germline Transmission:  Earliest citation of germline transmission: J:156169
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Conditional ready, No functional change)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThis allele was generated by inserting an EGFP-IRES-LoxP-Frt sequence into the 5' UTR of the En2 locus immediately upstream of the ATG and a LoxP site into the intron. An Frt-flanked neo cassette was removed by Flp mediated recombination.
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any En2 Mutation:  96 strains or lines available
Original:  J:156169 Cheng Y, et al., The Engrailed homeobox genes determine the different foliation patterns in the vermis and hemispheres of the mammalian cerebellum. Development. 2010 Feb;137(3):519-29
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.04
The Jackson Laboratory