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Mrotm1H
Targeted Allele Detail
Nomenclature
Symbol: Mrotm1H
Name: maestro; targeted mutation 1, Harwell
MGI ID: MGI:3831006
Gene: Mro  Location: Chr18:73859385-73881333 bp, + strand  Genetic Position: Chr18, 50.21 cM, cytoband E2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:144349
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 5 through 9, which contain the 4 heat domains, were replaced with a lacZ and neo cassette. The absence of transcript expression was confirmed by RT-PCR on male embryonic gonad extracts. (J:144349)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mro Mutation:  7 strains or lines available
Notes
ES cell line = 48/1
References
Original:  J:144349 Smith L, et al., The Maestro (Mro) gene is dispensable for normal sexual development and fertility in mice. PLoS One. 2008;3(12):e4091
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/21/2017
MGI 6.08
The Jackson Laboratory