Bhlhe22^tm2(cre)Gan
Targeted Allele Detail

Summary

• Symbol: Bhlhe22^tm2(cre)Gan
• Name: basic helix-loop-helix family, member e22; targeted mutation 2, Lin Gan
• MGI ID: MGI:3830517
• Synonyms: Bhlh5^cre
• Gene: Bhlhe22 Location: Chr3:18108489-18111678 bp, + strand Genetic Position: Chr3, 4.98 cM, cytoband A2
• Alliance: Bhlhe22^tm2(cre)Gan page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:144066
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutations: Insertion, Intragenic deletion
• Bhlhe22^tm2(cre)Gan expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Bhlhe22 (MGI:1930001)

• The coding region was replaced with a nuclear cre coding region. (J:144066)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Bhlhe22 (mouse) Summary of all recombinase alleles driven by Bhlhe22. Comparative matrix view of recombinase activities Alliance mouse Bhlhe22 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bhlhe22 Mutation: 12 strains or lines available

References

• Original: J:144066 Joshi PS, et al., Bhlhb5 regulates the postmitotic acquisition of area identities in layers II-V of the developing neocortex. Neuron. 2008 Oct 23;60(2):258-72
• All: 5 reference(s)