Crkl^tm1Cur
Targeted Allele Detail

Summary

• Symbol: Crkl^tm1Cur
• Name: v-crk avian sarcoma virus CT10 oncogene homolog-like; targeted mutation 1, Tom Curran
• MGI ID: MGI:3830004
• Synonyms: Crk-L^f
• Gene: Crkl Location: Chr16:17269851-17305298 bp, + strand Genetic Position: Chr16, 10.82 cM
• Alliance: Crkl^tm1Cur page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:143049
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 1 and a floxed neo cassette was inserted downstream of exon 1. (J:143049)

Expression

In Mice Carrying this Mutation:	24 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Crkl Mutation: 15 strains or lines available

References

• Original: J:143049 Park TJ, et al., Crk and Crk-like play essential overlapping roles downstream of disabled-1 in the Reelin pathway. J Neurosci. 2008 Dec 10;28(50):13551-62
• All: 8 reference(s)