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Tg(YAC18)18Hay
Transgene Detail
Nomenclature
Symbol: Tg(YAC18)18Hay
Name: transgene insertion 18, Michael Hayden
MGI ID: MGI:3829789
Transgene: Tg(YAC18)18Hay  Location: unknown  
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(YAC18)18Hay expresses 1 gene
 
Mutation detailsA YAC containing a full-length human huntingtin gene was used to generate transgenic mice. The endogenous human HTT promoter directed expression in many tissues with levels in the brain and testes being the highest. (J:55405)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:55405 Hodgson JG, et al., A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration. Neuron. 1999 May;23(1):181-92
All:  14 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory