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Runx2tm1.1Jals
Targeted Allele Detail
Nomenclature
Symbol: Runx2tm1.1Jals
Name: runt related transcription factor 2; targeted mutation 1.1, Janet L Stein
MGI ID: MGI:3829608
Synonyms: Runx2loxp7
Gene: Runx2  Location: Chr17:44495987-44814797 bp, - strand  Genetic Position: Chr17, 21.33 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:143532
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprtb-m2
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsGerm line, cre-mediated recombination was used to remove the neo cassette. No expression of truncated transcripts is observed. (J:143532)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Runx2 Mutation:  2 strains or lines available
References
Original:  J:143532 Lou Y, et al., A Runx2 threshold for the cleidocranial dysplasia phenotype. Hum Mol Genet. 2009 Feb 1;18(3):556-68
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/23/2015
MGI 5.22
The Jackson Laboratory