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Lrig3tm1.1Good
Targeted Allele Detail
Nomenclature
Symbol: Lrig3tm1.1Good
Name: leucine-rich repeats and immunoglobulin-like domains 3; targeted mutation 1.1, Lisa Goodrich
MGI ID: MGI:3829388
Gene: Lrig3  Location: Chr10:125966219-126015359 bp, + strand  Genetic Position: Chr10, 73.66 cM, cytoband D3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:142510
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsGerm line, cre-mediated recombination was used to remove exon 1. The absence of transcript expression was confirmed (data not shown). (J:142510)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 assay results
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lrig3 Mutation:  48 strains or lines available
References
Original:  J:142510 Abraira VE, et al., Cross-repressive interactions between Lrig3 and netrin 1 shape the architecture of the inner ear. Development. 2008 Dec;135(24):4091-9
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
04/13/2021
MGI 6.16
The Jackson Laboratory