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Ffar3tm1Reh
Targeted Allele Detail
Nomenclature
Symbol: Ffar3tm1Reh
Name: free fatty acid receptor 3; targeted mutation 1, Robert E Hammer
MGI ID: MGI:3829251
Synonyms: Gpr41-
Gene: Ffar3  Location: Chr7:30854330-30856178 bp, - strand  Genetic Position: Chr7, 19.25 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:143567
Parent Cell Line:  SM1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe coding region was replaced with a nuclear localized lacZ gene and floxed neo cassette. The absence of transcript expression was confirmed by RT-PCR on ileum extracts. (J:143567)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ffar3 Mutation:  6 strains or lines available
References
Original:  J:143567 Samuel BS, et al., Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41. Proc Natl Acad Sci U S A. 2008 Oct 28;105(43):16767-72
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory