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Ptrftm1Pfp
Targeted Allele Detail
Nomenclature
Symbol: Ptrftm1Pfp
Name: polymerase I and transcript release factor; targeted mutation 1, Paul F Pilch
MGI ID: MGI:3829005
Synonyms: Cavin-, Cavin1-
Gene: Ptrf  Location: Chr11:100956733-100970887 bp, - strand  Genetic Position: Chr11, 63.95 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:143425
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ptrf Mutation:  4 strains or lines available
References
Original:  J:143425 Liu L, et al., Deletion of Cavin/PTRF causes global loss of caveolae, dyslipidemia, and glucose intolerance. Cell Metab. 2008 Oct;8(4):310-7
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory