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Gstm1tm1Kfuj
Targeted Allele Detail
Nomenclature
Symbol: Gstm1tm1Kfuj
Name: glutathione S-transferase, mu 1; targeted mutation 1, Kazunori Fujimoto
MGI ID: MGI:3828070
Gene: Gstm1  Location: Chr3:108012255-108017973 bp, - strand  Genetic Position: Chr3, 46.83 cM, cytoband F3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:143553
Parent Cell Line:  W9.5/W95 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe entire gene, exons 1 through 8, was replaced with a neomycin selection cassette. No mRNA was detected in the liver of homozygotes by RT-PCR. (J:143553)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gstm1 Mutation:  8 strains or lines available
References
Original:  J:143553 Fujimoto K, et al., Characterization of phenotypes in Gstm1-null mice by cytosolic and in vivo metabolic studies using 1,2-dichloro-4-nitrobenzene. Drug Metab Dispos. 2006 Sep;34(9):1495-501
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/21/2017
MGI 6.08
The Jackson Laboratory