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Targeted Allele Detail
Symbol: Gstm1tm1Kfuj
Name: glutathione S-transferase, mu 1; targeted mutation 1, Kazunori Fujimoto
MGI ID: MGI:3828070
Gene: Gstm1  Location: Chr3:107919571-107925289 bp, - strand  Genetic Position: Chr3, 46.83 cM, cytoband F3
Germline Transmission:  Earliest citation of germline transmission: J:143553
Parent Cell Line:  W9.5/W95 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThe entire gene, exons 1 through 8, was replaced with a neomycin selection cassette. No mRNA was detected in the liver of homozygotes by RT-PCR. (J:143553)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gstm1 Mutation:  17 strains or lines available
Original:  J:143553 Fujimoto K, et al., Characterization of phenotypes in Gstm1-null mice by cytosolic and in vivo metabolic studies using 1,2-dichloro-4-nitrobenzene. Drug Metab Dispos. 2006 Sep;34(9):1495-501
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.17
The Jackson Laboratory