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Dock5Gt(AN0268)Wtsi
Gene trapped Allele Detail
Nomenclature
Symbol: Dock5Gt(AN0268)Wtsi
Name: dedicator of cytokinesis 5; gene trap AN0268, Wellcome Trust Sanger Institute
MGI ID: MGI:3828069
Synonyms: D5-
Gene: Dock5  Location: Chr14:67989584-68170891 bp, - strand  Genetic Position: Chr14, 34.66 cM
Mutation
origin
Mutant Cell Line:  AN0268
Germline Transmission:  Earliest citation of germline transmission: J:143342
Parent Cell Line:  E14TG2a.4 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Project Collection: Sanger Inst. Gene Trap Res.
Mutation
description
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector     Vector: pGT0lxr
 
Mutation detailsThe gene trap vector pGTOlxr, which contains a beta-geo cassette, was inserted into intron 29. The absence of protein expression was confirmed by western blot analysis. (J:143342)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 12 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Dock5 Mutation:  128 strains or lines available
References
Original:  J:143342 Laurin M, et al., The atypical Rac activator Dock180 (Dock1) regulates myoblast fusion in vivo. Proc Natl Acad Sci U S A. 2008 Oct 7;105(40):15446-51
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/18/2022
MGI 6.17
The Jackson Laboratory