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Dock1tm1Jfco
Targeted Allele Detail
Nomenclature
Symbol: Dock1tm1Jfco
Name: dedicator of cytokinesis 1; targeted mutation 1, Jean-Francois Cote
MGI ID: MGI:3828065
Gene: Dock1  Location: Chr7:134670654-135173639 bp, + strand  Genetic Position: Chr7, 79.14 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:143342
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 1 was replaced with a neomycin resistance cassette. The absence of protein expression was confirmed by western blot analysis. (J:143342)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dock1 Mutation:  79 strains or lines available
References
Original:  J:143342 Laurin M, et al., The atypical Rac activator Dock180 (Dock1) regulates myoblast fusion in vivo. Proc Natl Acad Sci U S A. 2008 Oct 7;105(40):15446-51
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory