About   Help   FAQ
Dock1tm1Jfco
Targeted Allele Detail
Nomenclature
Symbol: Dock1tm1Jfco
Name: dedicator of cytokinesis 1; targeted mutation 1, Jean-Francois Cote
MGI ID: MGI:3828065
Gene: Dock1  Location: Chr7:134670654-135173639 bp, + strand  Genetic Position: Chr7, 79.14 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:143342
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 1 was replaced with a neomycin resistance cassette. The absence of protein expression was confirmed by western blot analysis. (J:143342)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dock1 Mutation:  79 strains or lines available
References
Original:  J:143342 Laurin M, et al., The atypical Rac activator Dock180 (Dock1) regulates myoblast fusion in vivo. Proc Natl Acad Sci U S A. 2008 Oct 7;105(40):15446-51
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
03/21/2017
MGI 6.08
The Jackson Laboratory