Rrad^tm1Yec
Targeted Allele Detail

Summary

• Symbol: Rrad^tm1Yec
• Name: Ras-related associated with diabetes; targeted mutation 1, Yuqing E Chen
• MGI ID: MGI:3827009
• Gene: Rrad Location: Chr8:105354702-105357959 bp, - strand Genetic Position: Chr8, 53.04 cM
• Alliance: Rrad^tm1Yec page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:143140
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 2 was replaced by a neomycin resistance cassette. Protein product is not present in the heart of homozygous mice. (J:143140)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rrad Mutation: 13 strains or lines available

References

• Original: J:143140 Chang L, et al., Rad GTPase deficiency leads to cardiac hypertrophy. Circulation. 2007 Dec 18;116(25):2976-83
• All: 4 reference(s)