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Rradtm1Yec
Targeted Allele Detail
Nomenclature
Symbol: Rradtm1Yec
Name: Ras-related associated with diabetes; targeted mutation 1, Yuqing E Chen
MGI ID: MGI:3827009
Gene: Rrad  Location: Chr8:104628070-104631327 bp, - strand  Genetic Position: Chr8, 53.04 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:143140
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 2 was replaced by a neomycin resistance cassette. Protein product is not present in the heart of homozygous mice. (J:143140)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rrad Mutation:  4 strains or lines available
References
Original:  J:143140 Chang L, et al., Rad GTPase deficiency leads to cardiac hypertrophy. Circulation. 2007 Dec 18;116(25):2976-83
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/13/2017
MGI 6.10
The Jackson Laboratory