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Hccstm1Tcc
Targeted Allele Detail
Nomenclature
Symbol: Hccstm1Tcc
Name: holocytochrome c synthetase; targeted mutation 1, Timothy C Cox
MGI ID: MGI:3826866
Gene: Hccs  Location: ChrX:169311530-169320371 bp, - strand  Genetic Position: ChrX, 78.98 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:143285
Parent Cell Line:  W9.5/W95 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 5 and a neo cassette with a 3' loxP site was inserted downstream of exon 7. (J:143285)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 5 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Hccs Mutation:  4 strains or lines available
References
Original:  J:143285 Drenckhahn JD, et al., Compensatory growth of healthy cardiac cells in the presence of diseased cells restores tissue homeostasis during heart development. Dev Cell. 2008 Oct;15(4):521-33
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/15/2019
MGI 6.14
The Jackson Laboratory