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Septin3tm1Wtr
Targeted Allele Detail
Nomenclature
Symbol: Septin3tm1Wtr
Name: septin 3; targeted mutation 1, William S Trimble
MGI ID: MGI:3822551
Gene: Septin3  Location: Chr15:82268802-82294574 bp, + strand  Genetic Position: Chr15, 38.56 cM, cytoband E2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:142823
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 2 through 5 were replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on bain extracts. (J:142823)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Septin3 Mutation:  2 strains or lines available
References
Original:  J:142823 Tsang CW, et al., Superfluous role of mammalian septins 3 and 5 in neuronal development and synaptic transmission. Mol Cell Biol. 2008 Dec;28(23):7012-29
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/23/2020
MGI 6.15
The Jackson Laboratory