Nalcn^tm1Dren
Targeted Allele Detail

Summary

• Symbol: Nalcn^tm1Dren
• Name: sodium leak channel, non-selective; targeted mutation 1, Dejian Ren
• MGI ID: MGI:3819819
• Gene: Nalcn Location: Chr14:123514046-123864556 bp, - strand Genetic Position: Chr14, 66.04 cM
• Alliance: Nalcn^tm1Dren page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:141581
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted 20 bp upstream of the translation initiation site and 360 bp into intron 1 rendering exon 1 floxed. (J:141581)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nalcn Mutation: 116 strains or lines available

References

• Original: J:141581 Lu B, et al., The neuronal channel NALCN contributes resting sodium permeability and is required for normal respiratory rhythm. Cell. 2007 Apr 20;129(2):371-83
• All: 2 reference(s)