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Tg(tetO-TAg,CMV-rtTA)123Yihu
Transgene Detail
Nomenclature
Symbol: Tg(tetO-TAg,CMV-rtTA)123Yihu
Name: transgene insertion 123, Yinghe Hu
MGI ID: MGI:3819437
Synonyms: pTRE-SV40Tag/pTet-on
Transgene: Tg(tetO-TAg,CMV-rtTA)123Yihu  Location: unknown  
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Inducible, Inserted expressed sequence, Transactivator)
Mutation:    Insertion
 
Mutation detailsTwo constructs, one containing the SV40 large T antigen (TAg) gene driven by the tetracycline responsive promoter element and the other containing the tetracycline responsive transactivator driven by the cytomegalovirus promoter, were co-injected into fertilized oocytes. Two lines (line 123 and line 144) were created. (J:141623)
Phenotypes
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Disease models
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:141623 Sun Q, et al., Involvement of insulin-like growth factor-insulin receptor signal pathway in the transgenic mouse model of medulloblastoma. Cancer Sci. 2008 Feb;99(2):234-40
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/12/2015
MGI 5.21
The Jackson Laboratory