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Hgstm2Tkh
Targeted Allele Detail
Nomenclature
Symbol: Hgstm2Tkh
Name: HGF-regulated tyrosine kinase substrate; targeted mutation 2, Nobuyuki Tanaka
MGI ID: MGI:3818694
Synonyms: hrsloxP
Gene: Hgs  Location: Chr11:120467635-120483979 bp, + strand  Genetic Position: Chr11, 84.16 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:141391
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hgs Mutation:  8 strains or lines available
References
Original:  J:141391 Tamai K, et al., Loss of hrs in the central nervous system causes accumulation of ubiquitinated proteins and neurodegeneration. Am J Pathol. 2008 Dec;173(6):1806-17
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory