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Targeted Allele Detail
Symbol: Mapk8ip3tm1Ysok
Name: mitogen-activated protein kinase 8 interacting protein 3; targeted mutation 1, Katsuji Yoshioka
MGI ID: MGI:3818507
Synonyms: jsap2loxP, jsapflox
Gene: Mapk8ip3  Location: Chr17:24897506-24936977 bp, - strand  Genetic Position: Chr17, 12.53 cM
Germline Transmission:  Earliest citation of germline transmission: J:141459
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsA floxed neo cassette was inserted downstream of exon 2 and an additional loxP site was inserted downstream of exon 4. Germ line, cre mediated recombination was used to remove the neo cassette leaving exons 3 and 4 floxed. (J:141459)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mapk8ip3 Mutation:  3 strains or lines available
Original:  J:141459 Iwanaga A, et al., Neural-specific ablation of the scaffold protein JSAP1 in mice causes neonatal death. Neurosci Lett. 2007 Dec 11;429(1):43-8
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory