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Lilrb4atm1Ttk
Targeted Allele Detail
Nomenclature
Symbol: Lilrb4atm1Ttk
Name: leukocyte immunoglobulin-like receptor, subfamily B, member 4A; targeted mutation 1, Toshiyuki Takai
MGI ID: MGI:3818260
Synonyms: Gp49B-
Gene: Lilrb4a  Location: Chr10:51367052-51372707 bp, + strand  Genetic Position: Chr10, 25.5 cM, cytoband B4
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:141234
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin selection cassette replaced the promoter and first exon of the gene locus. Gene inactivation was confirmed by a lack of protein on the surface of bone marrow derived dendritic cells. (J:141234)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Lilrb4a Mutation:  25 strains or lines available
References
Original:  J:141234 Kasai S, et al., A novel regulatory role of gp49B on dendritic cells in T-cell priming. Eur J Immunol. 2008 Sep;38(9):2426-37
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/27/2022
MGI 6.21
The Jackson Laboratory