About   Help   FAQ
Tg(CD2-Zbtb7b)C8Rbo
Transgene Detail
Nomenclature
Symbol: Tg(CD2-Zbtb7b)C8Rbo
Name: transgene insertion C8, Remy Bosselut
MGI ID: MGI:3817775
Synonyms: cKrox, ThPOK
Transgene: Tg(CD2-Zbtb7b)C8Rbo  Location: unknown  
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(CD2-Zbtb7b)C8Rbo expresses 1 gene
 
Mutation detailsCoding sequence for the Zbtb7b gene was placed under control of the human CD2 promoter and locus control region. This promoter drives expression in double-postive and single-positive thymocytes and in mature T cells. Three lines (C8, L4, L8) displaying similar phenotypes were established with the C8 line being chosen for further analysis. Transgene expression was confirmed in thymocytes by immunoprecipitation and immunoblotting. (J:97610)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:97610 Sun G, et al., The zinc finger protein cKrox directs CD4 lineage differentiation during intrathymic T cell positive selection. Nat Immunol. 2005 Apr;6(4):373-81
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
02/18/2020
MGI 6.14
The Jackson Laboratory