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Nr1i3tm1.1Arte
Targeted Allele Detail
Nomenclature
Symbol: Nr1i3tm1.1Arte
Name: nuclear receptor subfamily 1, group I, member 3; targeted mutation 1.1, TaconicArtemis
MGI ID: MGI:3815105
Gene: Nr1i3  Location: Chr1:171213970-171220701 bp, + strand  Genetic Position: Chr1, 79.21 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:140975
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsNearly all of the human sequence in Nr1i3tm1(NR1I3)Arte was deleted by germ line, phiC31 mediated recombination leaving only mouse exon 1 and human exon 2. ES cells originally used contained Nr1i2tm1(NR1I2)Arte. (J:140975)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 4 strains available      Cell Lines: 0 lines available
Carrying any Nr1i3 Mutation:  17 strains or lines available
References
Original:  J:140975 Scheer N, et al., A novel panel of mouse models to evaluate the role of human pregnane X receptor and constitutive androstane receptor in drug response. J Clin Invest. 2008 Sep;118(9):3228-39
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/27/2016
MGI 6.05
The Jackson Laboratory