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Hspa5tm1Alee
Targeted Allele Detail
Nomenclature
Symbol: Hspa5tm1Alee
Name: heat shock protein 5; targeted mutation 1, Amy S Lee
MGI ID: MGI:3814698
Synonyms: Grp78f, tri-loxP
Gene: Hspa5  Location: Chr2:34771970-34776531 bp, + strand  Genetic Position: Chr2, 22.94 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:111416
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
    A vector was designed to insert a floxed neo into intron 4 and a third loxP site into intron 7. (J:111416)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hspa5 Mutation:  6 strains or lines available
References
Original:  J:111416 Luo S, et al., GRP78/BiP is required for cell proliferation and protecting the inner cell mass from apoptosis during early mouse embryonic development. Mol Cell Biol. 2006 Aug;26(15):5688-97
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory