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Rac1tm1Atai
Targeted Allele Detail
Nomenclature
Symbol: Rac1tm1Atai
Name: RAS-related C3 botulinum substrate 1; targeted mutation 1, Atsu Aiba
MGI ID: MGI:3814355
Synonyms: rac1flox
Gene: Rac1  Location: Chr5:143505478-143528036 bp, - strand  Genetic Position: Chr5, 82.22 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:140575
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 1 and an frt flanked neo cassette with a 3' loxP site was inserted downstream of exon 1. Germ line, flp mediated recombination was used to remove the neo cassette leaving exon 1 floxed. (J:140575)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rac1 Mutation:  11 strains or lines available
References
Original:  J:140575 Kassai H, et al., Rac1 in cortical projection neurons is selectively required for midline crossing of commissural axonal formation. Eur J Neurosci. 2008 Jul;28(2):257-67
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
01/20/2015
MGI 5.21
The Jackson Laboratory