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Rap1atm1Laaq
Targeted Allele Detail
Nomenclature
Symbol: Rap1atm1Laaq
Name: RAS-related protein-1a; targeted mutation 1, Lawrence A Quilliam
MGI ID: MGI:3813936
Gene: Rap1a  Location: Chr3:105727267-105801336 bp, - strand  Genetic Position: Chr3, 46.45 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:140471
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 5 was replaced with a neo cassette. The absence of protein expression was confirmed by western blot on purified neutrophils and various organ extracts. (J:140471)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rap1a Mutation:  11 strains or lines available
References
Original:  J:140471 Li Y, et al., Rap1a null mice have altered myeloid cell functions suggesting distinct roles for the closely related Rap1a and 1b proteins. J Immunol. 2007 Dec 15;179(12):8322-31
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory