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Tg(THY1-SNCA*A53T)F53Sud
Transgene Detail
Nomenclature
Symbol: Tg(THY1-SNCA*A53T)F53Sud
Name: transgene insertion F53, Thomas C Sudhof
MGI ID: MGI:3811331
Synonyms: F53
Transgene: Tg(THY1-SNCA*A53T)F53Sud  Location: unknown  
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(THY1-SNCA*A53T)F53Sud expresses 1 gene
 
Mutation detailsThe transgenic construct carries the A53T mutant form of the human SNCA (synuclein, alpha) gene under the control of a human THY1 (thymus cell antigen 1, theta) promoter. Expression of the transgene is 10-fold increased in the brain and 20-fold in the spinal cord. (J:140019)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
References
Original:  J:140019 Sudhof TC, Generation of a mutant A53T human alpha-synuclein transgene. MGI Direct Data Submission. 2008;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/15/2020
MGI 6.15
The Jackson Laboratory