Cacng3^tm1Ran
Targeted Allele Detail

Summary

• Symbol: Cacng3^tm1Ran
• Name: calcium channel, voltage-dependent, gamma subunit 3; targeted mutation 1, Roger A Nicoll
• MGI ID: MGI:3810416
• Synonyms: gamma-3^-, TARP gamma-3^-
• Gene: Cacng3 Location: Chr7:122270967-122368616 bp, + strand Genetic Position: Chr7, 66.81 cM, cytoband F3
• Alliance: Cacng3^tm1Ran page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:138791
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neo-cassette replaced exon 2 and part of 3 via homologous recombination. Immunoblot analysis of brain lysates from homozygous mice confirmed the absence of protein. (J:138791)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cacng3 Mutation: 16 strains or lines available

References

• Original: J:138791 Menuz K, et al., TARP redundancy is critical for maintaining AMPA receptor function. J Neurosci. 2008 Aug 27;28(35):8740-6
• All: 2 reference(s)