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Kif5ctm1Gsn
Targeted Allele Detail
Nomenclature
Symbol: Kif5ctm1Gsn
Name: kinesin family member 5C; targeted mutation 1, Lawrence SB Goldstein
MGI ID: MGI:3809823
Gene: Kif5c  Location: Chr2:49619298-49774778 bp, + strand  Genetic Position: Chr2, 28.68 cM, cytoband C
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:139716
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA 2 kb pGK-neo cassette replaces exon 3 of the gene. Full-length protein and mRNA are completely absent in homozygous brain as determined by northern and western blotting, but a truncated 5' mRNA and protein fragment have been detected. (J:139716)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Kif5c Mutation:  19 strains or lines available
References
Original:  J:139716 Goldstein LS, Generation of a Kif5C null allele. MGI Direct Data Submission. 2008;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory