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Adam10tm1.1Zhu
Targeted Allele Detail
Nomenclature
Symbol: Adam10tm1.1Zhu
Name: a disintegrin and metallopeptidase domain 10; targeted mutation 1.1, Yuan Zhuang
MGI ID: MGI:3809599
Gene: Adam10  Location: Chr9:70678997-70780229 bp, + strand  Genetic Position: Chr9, 39.53 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:139042
Parent Cell Line:  W4 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Germ line, cre mediated recombination was used to remove exon 3. (J:139042)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Adam10 Mutation:  25 strains or lines available
References
Original:  J:139042 Tian L, et al., ADAM10 is essential for proteolytic activation of Notch during thymocyte development. Int Immunol. 2008 Sep;20(9):1181-7
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/14/2017
MGI 6.11
The Jackson Laboratory