About   Help   FAQ
Gapttm1.1Wz
Targeted Allele Detail
Nomenclature
Symbol: Gapttm1.1Wz
Name: Grb2-binding adaptor, transmembrane; targeted mutation 1.1, Weiguo Zhang
MGI ID: MGI:3809581
Synonyms: GAPT-
Gene: Gapt  Location: Chr13:110352616-110357199 bp, - strand  Genetic Position: Chr13, 61.87 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:138146
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsGerm line, cre mediated recombination was used to remove the coding exon and neo cassette. The absence of protein expression was confirmed by western blot analysis on bone marrow and spleen extracts. (J:138146)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gapt Mutation:  12 strains or lines available
References
Original:  J:138146 Liu Y, et al., Identification of a new transmembrane adaptor protein that constitutively binds Grb2 in B cells. J Leukoc Biol. 2008 Sep;84(3):842-51
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
06/18/2019
MGI 6.14
The Jackson Laboratory