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Sox2tm1Okud
Targeted Allele Detail
Summary
Symbol: Sox2tm1Okud
Name: SRY (sex determining region Y)-box 2; targeted mutation 1, Akihiko Okuda
MGI ID: MGI:3809487
Synonyms: Sox2FL
Gene: Sox2  Location: Chr3:34704554-34706610 bp, + strand  Genetic Position: Chr3, 16.93 cM, cytoband A2-B
Alliance: Sox2tm1Okud page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:138323
Parent Cell Line:  E14TG2a (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutations:    Insertion, Intragenic deletion
    The mouse Sox2 ORF was replaced with IREShygTKpA cassette flanked by loxP sites. (J:138323)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sox2 Mutation:  47 strains or lines available
References
Original:  J:138323 Miyagi S, et al., Consequence of the loss of Sox2 in the developing brain of the mouse. FEBS Lett. 2008 Aug 6;582(18):2811-5
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/22/2022
MGI 6.22
The Jackson Laboratory