About   Help   FAQ
Targeted Allele Detail
Symbol: Sox2tm1Okud
Name: SRY (sex determining region Y)-box 2; targeted mutation 1, Akihiko Okuda
MGI ID: MGI:3809487
Synonyms: Sox2FL
Gene: Sox2  Location: Chr3:34704554-34706610 bp, + strand  Genetic Position: Chr3, 16.93 cM, cytoband A2-B
Alliance: Sox2tm1Okud page
Germline Transmission:  Earliest citation of germline transmission: J:138323
Parent Cell Line:  E14TG2a (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Conditional ready, No functional change)
Mutations:    Insertion, Intragenic deletion
    The mouse Sox2 ORF was replaced with IREShygTKpA cassette flanked by loxP sites. (J:138323)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sox2 Mutation:  47 strains or lines available
Original:  J:138323 Miyagi S, et al., Consequence of the loss of Sox2 in the developing brain of the mouse. FEBS Lett. 2008 Aug 6;582(18):2811-5
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Copyright, and Privacy Statement
Send questions and comments to User Support.
last database update
MGI 6.22
The Jackson Laboratory