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Ffar2tm1Lex
Targeted Allele Detail
Nomenclature
Symbol: Ffar2tm1Lex
Name: free fatty acid receptor 2; targeted mutation 1, Lexicon Genetics
MGI ID: MGI:3808703
Synonyms: GPR43 KO
Gene: Ffar2  Location: Chr7:30818348-30823775 bp, - strand  Genetic Position: Chr7, 19.25 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:138134
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S5/SvEvBrd
Project Collection: Lexicon
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    The exon containing the entire coding region was replaced with a neo selection cassette. (J:138134)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ffar2 Mutation:  10 strains or lines available
References
Original:  J:138134 Ge H, et al., Activation of g protein-coupled receptor 43 in adipocytes leads to inhibition of lipolysis and suppression of plasma free Fatty acids. Endocrinology. 2008 Sep;149(9):4519-26
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/18/2018
MGI 6.12
The Jackson Laboratory