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Nfasctm1.1Brp
Targeted Allele Detail
Nomenclature
Symbol: Nfasctm1.1Brp
Name: neurofascin; targeted mutation 1.1, Peter J Brophy
MGI ID: MGI:3808598
Gene: Nfasc  Location: Chr1:132564690-132741797 bp, - strand  Genetic Position: Chr1, 57.42 cM
Reduced myelination in the Nfasctm1.1Brp/Nfasctm1.1Brp mouse at P6

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:107591
Parent Cell Line:  E14TG2aIV (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nfasc Mutation:  8 strains or lines available
References
Original:  J:107591 Sherman DL, et al., Neurofascins are required to establish axonal domains for saltatory conduction. Neuron. 2005 Dec 8;48(5):737-42
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory