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Cyp2r1tm1(KOMP)Vlcg
Targeted Allele Detail
Nomenclature
Symbol: Cyp2r1tm1(KOMP)Vlcg
Name: cytochrome P450, family 2, subfamily r, polypeptide 1; targeted mutation 1, Velocigene
MGI ID: MGI:3808340
Synonyms: Cyp2r1-, Cyp2r1tm1Vlcg
Gene: Cyp2r1  Location: Chr7:114149358-114162283 bp, - strand  Genetic Position: Chr7, 59.79 cM
Mutation
origin
Mutant Cell Lines:  10568A-D10, 10568A-E11, 10568A-G3
Germline Transmission:  Earliest citation of germline transmission: J:223194
Parent Cell Line:  VGB6 (ES Cell)
Strain of Origin:  C57BL/6NTac
Project Collection: KOMP-Regeneron
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion     Vector: ZEN-Ub1
 
Mutation detailsA 12.9-kb span between positions 114149312-114162189 of Chromosome 7 (Build GRCm39), which covers all 5 exons of the gene, was replaced with a beta-galactosidase coding sequence (lacZ) and a neomycin selection cassette. (J:136110, J:223194)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 1 line available
Carrying any Cyp2r1 Mutation:  14 strains or lines available
References
Original:  J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/04/2022
MGI 6.17
The Jackson Laboratory