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Sox1tm1(cre)Take
Targeted Allele Detail
Nomenclature
Symbol: Sox1tm1(cre)Take
Name: SRY (sex determining region Y)-box 1; targeted mutation 1, Takumi Era
MGI ID: MGI:3807952
Synonyms: Sox1-Cre
Gene: Sox1  Location: Chr8:12395519-12399555 bp, + strand  Genetic Position: Chr8, 5.73 cM, cytoband A1-A2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:138918
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Mutation detailsCre recombines cDNA was inserted into the ATG codon start site of Sox1 by in-frame. PGK-NEO cassette was removed by transient Flp recombinase expression. (J:138918)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Sox1     Summary of all recombinase alleles driven by Sox1.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sox1 Mutation:  1 strain or line available
References
Original:  J:138918 Takashima Y, et al., Neuroepithelial cells supply an initial transient wave of MSC differentiation. Cell. 2007 Jun 29;129(7):1377-88
All:  15 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory