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Spi1tm1.1Rpd
Targeted Allele Detail
Nomenclature
Symbol: Spi1tm1.1Rpd
Name: spleen focus forming virus (SFFV) proviral integration oncogene; targeted mutation 1.1, Rodney P DeKoter
MGI ID: MGI:3806995
Synonyms: Sfpi1Blac
Gene: Spi1  Location: Chr2:91082390-91115756 bp, + strand  Genetic Position: Chr2, 50.44 cM, cytoband E3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:138501
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Hypomorph, Reporter)
Mutation:    Insertion
 
Mutation detailsGerm line, cre mediated recombination was used to remove the neo cassette leaving the beta-lactamase intact. This is a hypomorphic allele. (J:138501)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Spi1 Mutation:  12 strains or lines available
References
Original:  J:138501 Kamath MB, et al., Dose-dependent repression of T-cell and natural killer cell genes by PU.1 enforces myeloid and B-cell identity. Leukemia. 2008 Jun;22(6):1214-25
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/23/2017
MGI 6.09
The Jackson Laboratory