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Icam4tm1Jach
Targeted Allele Detail
Nomenclature
Symbol: Icam4tm1Jach
Name: intercellular adhesion molecule 4, Landsteiner-Wiener blood group; targeted mutation 1, Joel Anne Chasis
MGI ID: MGI:3806488
Gene: Icam4  Location: Chr9:21029373-21030531 bp, + strand  Genetic Position: Chr9, 7.69 cM, cytoband A3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:138068
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 1 through 3 were replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis of erythrocyte extracts. (J:138068)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Icam4 Mutation:  4 strains or lines available
References
Original:  J:138068 Lee G, et al., Targeted gene deletion demonstrates that the cell adhesion molecule ICAM-4 is critical for erythroblastic island formation. Blood. 2006 Sep 15;108(6):2064-71
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/14/2017
MGI 6.11
The Jackson Laboratory