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Tg(MC1R)1Jkn
Transgene Detail
Nomenclature
Symbol: Tg(MC1R)1Jkn
Name: transgene insertion 1, Ian J Jackson
MGI ID: MGI:3805878
Synonyms: Tg-MC1R
Transgene: Tg(MC1R)1Jkn  Location: unknown  
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsThe transgene strain was created by microinjection of the human BAC RPCI11-655K11 into embryos homozygous for Mc1re. The BAC contains 146 kb of sequence with the complete human gene MC1R and includes at least 4 other genes. Quantitative RT-PCR on skin samples indicated that expression of the human MC1R was 9- to 20-fold lower than the endogenous mouse gene. (J:129904)
Phenotypes
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Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:129904 Jackson IJ, et al., Humanized MC1R transgenic mice reveal human specific receptor function. Hum Mol Genet. 2007 Oct 1;16(19):2341-8
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory