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Tnnt2tm1Feah
Targeted Allele Detail
Nomenclature
Symbol: Tnnt2tm1Feah
Name: troponin T2, cardiac; targted mutation 1, Fehaan Ahmad
MGI ID: MGI:3805012
Gene: Tnnt2  Location: Chr1:135836354-135852260 bp, + strand  Genetic Position: Chr1, 59.32 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:137964
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 14 was replaced with a floxed neo cassette. Germ line, cre mediated recombination was used to remove the neo cassette. The absence of transcript expression was confirmed by northern blot analysis on embryo extracts. (J:137964)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tnnt2 Mutation:  6 strains or lines available
References
Original:  J:137964 Ahmad F, et al., The role of cardiac troponin T quantity and function in cardiac development and dilated cardiomyopathy. PLoS ONE. 2008;3(7):e2642
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/17/2015
MGI 5.21
The Jackson Laboratory