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Targeted Allele Detail
Symbol: Mib1tm2Kong
Name: mindbomb E3 ubiquitin protein ligase 1; targeted mutation 1, Young-Yun Kong
MGI ID: MGI:3804448
Synonyms: Mib1f
Gene: Mib1  Location: Chr18:10725548-10818704 bp, + strand  Genetic Position: Chr18, 5.35 cM
Germline Transmission:  Earliest citation of germline transmission: J:130369
Parent Cell Line:  E14K (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsA loxP site was inserted upstream of exon 2 and an frt-flanked neo cassette with a 5' loxP site was inserted downstream of exon 3. Flp-mediated recombination was used to remove the neo cassette leaving exons 2 and 3 floxed. (J:130369)
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mib1 Mutation:  21 strains or lines available
Original:  J:130369 Koo BK, et al., An obligatory role of mind bomb-1 in notch signaling of Mammalian development. PLoS One. 2007;2(11):e1221
All:  13 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.03
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