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Kremen2tm1Cni
Targeted Allele Detail
Nomenclature
Symbol: Kremen2tm1Cni
Name: kringle containing transmembrane protein 2; targeted mutation 1, Christof Niehrs
MGI ID: MGI:3804431
Gene: Kremen2  Location: Chr17:23741200-23745829 bp, - strand  Genetic Position: Chr17, 12.03 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:137914
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 1 through 5 were replaced with a lacZ and neo cassette. The absence of transcript expression was confirmed by whole mount in situ hybridization. (J:137914)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kremen2 Mutation:  12 strains or lines available
References
Original:  J:137914 Ellwanger K, et al., Targeted disruption of the Wnt regulator Kremen induces limb defects and high bone density. Mol Cell Biol. 2008 Aug;28(15):4875-82
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/18/2017
MGI 6.08
The Jackson Laboratory