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Kremen1tm1Dgen
Targeted Allele Detail
Nomenclature
Symbol: Kremen1tm1Dgen
Name: kringle containing transmembrane protein 1; targeted mutation 1, Deltagen
MGI ID: MGI:3804430
Gene: Kremen1  Location: Chr11:5191552-5261558 bp, - strand  Genetic Position: Chr11, 3.36 cM, cytoband A1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:137914
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Project Collection: Deltagen
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 2 was replaced with a LacZ and neo cassette. The absence of protein expression was confirmed by western blot analysis on lung and liver extracts. (J:137914)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kremen1 Mutation:  26 strains or lines available
References
Original:  J:137914 Ellwanger K, et al., Targeted disruption of the Wnt regulator Kremen induces limb defects and high bone density. Mol Cell Biol. 2008 Aug;28(15):4875-82
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/12/2017
MGI 6.10
The Jackson Laboratory